Angst

Defined in the dictionary as:

a feeling of dread, anxiety or anguish.

Defined in music by the following. Note the need for both an anguish-filled voice and heart-breaking, gut-wrenching lyrics in equal parts:

I can't keep holding on

To what you've got

When all you've got is hurt

                                        - U2, "One"

And I don't know why you couldn't just stay with me

You couldn't stand to be near me when my face don't seem to wanna shine

'Cause it's a little bit dirty

                                        - Matchbox 20, "Push"

Oh my God, you can't believe, it's happening again

Your baby's gone and you're all alone and it looks like the end

                                        - Eagles, "Wasted Time" 

When it's good, then it's good, it's so good 'til it goes bad
'Til you're trying to find the you that you once had
I have heard myself cry, "Never again"
Broken down in agony just trying to find a friend
                                        - P!nk, "Sober"

If she ever tries to fucking leave again
Gonna tie her to the bed and set the house on fire
                                        - Eminem, "Love the Way You Lie"